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New 'dementia atlas' reveals disparity in care across England

This is the area of the brain which is involved in laying down memories. If you start putting on weight, levels of ghrelin drop and brain cell replacement slows. The good news is that this brain-cell damage can be reversed by the two-day fasting regime, although so far Professor Mattson has shown this only in rats. A human trial is starting soon.

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There is reason to think it should work. Fasting every other day had a striking effect on people with asthma in a small study he ran a few years ago.


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Tests showed that levels of inflammation markers had dropped by 90 per cent. But he cautions that patients have to stick to the diet, as symptoms began to return two weeks after giving it up.


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  • Not everyone will find fasting intermittently is something they can manage. It gives us another option.

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    My experience is men seem to adapt better to it than women. But Professor Mattson believes these new fasting regimes could help tackle our failure to live more healthily. Dr Susan Jebb, head of diet and population health at the Medical Research Council agrees that losing weight is about the healthiest thing many of us can do.

    But whether fasting could be used as a way of treating people at raised risk of heart disease or dementia, it is really too early to say, adds Dr Jebb. So is there any harm in trying a little intermittent fasting ourselves? As a result of his research, Professor Mattson now keeps his own calorie intake down.


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    • However, Dr Jebb advises against fasting. If people have been heavily restricted for a couple of days they might feel that gave them a licence to over-eat.

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      Meanwhile the British Dietetic Association has warned that frequent fasting could raise the risk of osteoporosis and infertility. If the benefits are as big as the research suggests, there may be many willing to try it. But experts advise always speaking to your doctor before embarking on such a regimen. The views expressed in the contents above are those of our users and do not necessarily reflect the views of MailOnline.

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